Main Fight Card:
- Georges St. Pierre (170) vs. lightweight champ B.J. Penn (168) (Welterweight Title Fight)
- Lyoto Machida (206) vs. Thiago Silva (206)
- Karo Parisyan (170) vs. Dong Hyun Kim (171)
- Nate Diaz (156) vs. Clay Guida (156)
- Stephan Bonnar (206) vs. Jon Jones (206)
Preliminary Fight Card:
- Jon Fitch (171) vs. Akihiro Gono (171)
- Manny Gamburyan (155) vs. Thiago Tavares (155)
- John Howard (171) vs. Chris Wilson (170)
- Jake O'Brien (205) vs. Christian Wellisch (206)
- Matt Arroyo (171) vs. Dan Cramer (171)